WHO functional class II-III Pulmonary arterial hypertension

What is WHO Functional Class II-III Pulmonary arterial hypertension?

Pulmonary Arterial Hypertension (PAH) is a rare, progressive disorder of the lungs in which the pulmonary arteries are constricted and the heart is burdened, leading to reduced oxygen and increased blood pressure in the lungs. It is classified according to the World Health Organization (WHO) functional class, with class II and class III being the most severe classes of the disorder. Symptoms of PAH in these classes include shortness of breath, fatigue, chest pain, and dizziness.

Treatment of WHO Class II-III PAH

The goal of treatment in WHO class II-III PAH is to reduce or prevent the symptoms and progression of the disease. A multidisciplinary approach is often used, including pharmacotherapy, lifestyle modifications, and supportive care. Commonly prescribed medications include prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors, and combination therapy.

Lifestyle modifications for WHO Class II-III PAH

In addition to taking medications, lifestyle modifications are important to managing WHO class II-III PAH. It is important to maintain a healthy diet and lifestyle, including regular exercise. Stress can worsen PAH symptoms, so it is important to find ways to reduce stress and manage emotional issues. It is also important to monitor symptoms and adjust treatment as needed.

Supportive care

Supportive care is also important for managing WHO class II-III PAH. This can include regular monitoring of disease progression and overall quality of life. It is important to communicate openly and honestly with the healthcare team, including family members and carers, regarding any changes in symptoms or lifestyle.

Supportive care can also include providing emotional and psychological support. Keep in mind that the diagnosis is not something that can be easily overcome, and that emotional support is just as important as physical care.


WHO class II-III Pulmonary arterial hypertension is a serious condition that requires careful management. With proper treatment, lifestyle modifications, and supportive care, it is possible to manage and reduce the symptoms of PAH. It is important to be in close contact with a healthcare provider to ensure that treatment is safe and effective.