Skin lesion aspiration

What is a Skin Lesion Aspiration?

The skin lesion aspiration procedure is a type of skin biopsy on a lesion. The procedure involves taking a tissue sample from a bump, mole, or other lesion on the skin and examining it under a microscope for any signs of an infection or abnormal growth. Skin lesion aspirations can provide useful information that can help with the diagnosis and treatment of a wide range of skin conditions.


Before a skin lesion aspiration, it’s important for the doctor to obtain as much information as possible about the lesion. This includes:

  • Detailed medical history
  • Size, shape, color, and texture of the lesion
  • Location on the body
  • Pain or other symptoms (e.g. itching) associated with the lesion

The doctor may take digital pictures of the patient’s lesions for use in a medical record or for comparison as the condition progresses or changes.


During the procedure, the doctor will use a syringe to withdraw fluid or cell samples from the lesion. Depending on the type and size of the lesion, the doctor may use a scalpel to scrape away a small amount of tissue. These samples are then put on microscope slides for further examination.

Types of Skin Lesions

There are a number of different types of skin lesions, including:

  • Actinic keratoses
  • Basal cell carcinomas
  • Lentigines
  • Moles
  • Nodules
  • Seborrheic keratoses
  • Squamous cell carcinomas
  • Vitiligo
  • Warts

The type and/or size of lesion may determine whether a skin lesion aspiration or a different type of biopsy will be necessary.


The skin lesion aspiration procedure is generally considered to be safe and carries minimal risks. Possible risks include:

  • Infection
  • Scarring
  • Bleeding

It is important to ensure that the doctor performing the procedure is experienced in this type of procedure.

Why it is necessary?

The purpose of a skin lesion aspiration is to identify infections and/or abnormal growths and help to determine a diagnosis and appropriate treatment. In some cases, the procedure may also be used to confirm the diagnosis of a skin condition or monitor the progress of a particular skin condition.

When to Undergo the Procedure?

Skin lesion aspirations may be recommended by a doctor in any of the following situations:

  • You have a lesion that appears to be an infection
  • You have a suspicious-looking mole or skin growth
  • There is a change in size, shape, color, or texture of a mole or skin growth
  • You have a lesion that has not responded to treatment
  • You have a family history of skin cancer

A skin lesion aspiration is an important tool that can help to diagnose and/or monitor a wide range of skin conditions.