Ichthyosis Vulgaris

What is Ichthyosis Vulgaris?

Ichthyosis vulgaris is a common, inherited skin disorder. Those with ichthyosiform erythroderma, or ichthyosis vulgaris, have cells that produce too much keratin, leading to thickening of the skin layers and a build-up of dry, rough, scaly patches. It's often referred to as fish skin disease.

Symptoms of Ichthyosis Vulgaris

The symptoms of ichthyosis vulgaris can range from mild to severe, and include:

• Dry, rough patches of skin
• Flaky, ash-like scales on the skin
• Itchy skin
• Thickening of the skin
• Darkening of the skin

Cause of Ichthyosis Vulgaris

Ichthyosis vulgaris is caused by a mutation in a gene called filaggrin. This gene helps create a protective layer in the skin, called the acid mantle. People with a mutation in the filaggrin gene have a reduced amount of acid mantle, which makes the skin more prone to losing moisture and makes it difficult for the skin to protect itself from environmental pollutants and irritants.

Treatment of Ichthyosis Vulgaris

There’s no cure for ichthyosis vulgaris, but there are treatments available that can help manage the symptoms—like moisturizing lotions and creams and medicated ointments. Your doctor can also prescribe topical steroids or oral retinoids to help reduce the thickening of the skin.