Recurrent Cutaneous T-cell lymphoma

What is Recurrent Cutaneous T-cell Lymphoma?

Recurrent Cutaneous T-cell Lymphoma (RCTCL) is a rare, aggressive form of non-Hodgkin's lymphoma (NHL) that affects the skin.

RCTCL develops from T-cells, a type of white blood cell that plays an important role in the body's immune system. When these cells become abnormal, they start growing out of control. This causes a lesion or tumor to form on the skin.

Symptoms of Recurrent Cutaneous T-cell Lymphoma

The most common symptom of RCTCL is a persistent red patch or sore on the skin that does not heal. The patch is usually raised, scaly, and may contain ridges that can extend to other parts of the body. Often times, the patches can also be itchy and tender.

Other common symptoms of RCTCL include:

  • Fatigue
  • Weight loss
  • Night sweats
  • Fever
  • Enlarged lymph nodes

Diagnosis of Recurrent Cutaneous T-cell Lymphoma

To diagnose RCTCL, your doctor will perform a physical exam and ask about your medical history. Your doctor may also order blood tests and a biopsy of the affected skin.

A biopsy involves taking a small sample of cells from the skin and examining them under a microscope. Your doctor may also order imaging tests such as an X-ray, MRI, or CT scan to look for any signs of cancer in other parts of your body.

Treatment of Recurrent Cutaneous T-cell Lymphoma

Treatment for RCTCL typically includes chemotherapy and radiation therapy. These treatments can help reduce the size of the tumor and slow the progression of the disease.

Other treatments may include:

  • Immunotherapy
  • Targeted therapy
  • Surgery
  • Radiation therapy
  • Phototherapy


RCTCL is a rare condition and its long-term prognosis is not well known. However, with treatment, most patients can achieve remission and maintain a good quality of life.