metastatic gastroenteropancreatic neuroendocrine tumors

Metastatic Gastroenteropancreatic Neuroendocrine Tumours

Gastroenteropancreatic(GEP) neuroendocrine tumors(NETs) are a type of neuroendocrine cancer that originates in the GI tract, pancreas, or chest region and can spread to other organs.Gastroenteropancreatic neuroendocrine tumors (GEP NETs) can be slow-growing or aggressive, but all types have the ability to metastasize, or spread to other parts of the body. NETs are typically classified according to several factors, including location, grade, and size.

Symptoms of Metastatic GEP NETs

Metastatic GEP NETs can cause a variety of symptoms, depending on the location of the tumor and the progression of the disease. Common symptoms include:

Abdominal pain
Weight loss
Yellowing of the skin/whites of the eyes (jaundice)
Nausea and vomiting
Diarrhea
Fatigue
Changes in hormone levels, such as Cushing's syndrome, diabetes, or over- or under-activity of the thyroid gland

Diagnosis

Testing for GEP NETs involves several steps. Your doctor may recommend blood tests to check hormone levels, as well as imaging tests such as an MRI or CT scan to locate the tumor. If necessary, a biopsy can also be performed to get a sample of the tumor cells for further analysis. These tests will help your doctor determine the type and stage of the cancer and the best course of treatment.

Treatment Options for Metastatic GEP NETs

Treatment for metastatic GEP NETs will depend on the type and stage of the tumor, as well as your overall health. Common treatment options include:

Surgery to remove the tumor, if possible, or to reduce symptoms caused by the tumor
Radiation therapy to reduce tumor size and alleviate symptoms
Chemotherapy or other targeted therapies depending on the type and stage of the tumor
Clinical trials to explore options for advanced or recurrent tumors