Inoperable Adrenocortical carcinoma

Inoperable Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is a rare form of cancer that develops in the adrenal cortex, the outer layer of the adrenal gland. It is more common in children than in adults. Inoperable adrenocortical carcinoma (AAC) is a form of ACC that is very difficult to treat because the tumor is often situated deep in the abdomen and is intertwined with surrounding organs.

Patients with inoperable AAC usually are evaluated for aggressive systemic therapies including chemotherapy, hormone therapy, and other specialized treatments aimed at targeting the tumor.

Treating Inoperable ACC

Treating inoperable ACC often requires a team approach typically consisting of a medical oncologist, endocrinologist, and a radiation oncologist. Treatments may include the following:

• Chemotherapy: This is usually the first line of treatment for inoperable ACC. Depending on the particular situation, various types of chemotherapy may be used to target the tumor. This can be given either intravenously or orally.
• Hormone Therapy: Hormones may be used to target the cancerous cells in the tumor. It is important to monitor hormone levels closely in order to ensure the therapy is effective. In some cases, the hormones can actually cause the cancer to grow.
• Radiation Therapy: Radiation therapy may be used to shrink the size of the tumor or destroy cancerous cells. This can be an effective treatment when used in conjunction with chemotherapy.
• Surgery: Surgery may be an option for some people with inoperable ACC. Depending on the situation, the tumor may be removed, or it may be necessary to remove adjacent organs in order to avoid spreading the cancer.

These treatments may be used alone or in combination with each other in order to best attack the cancer.

Living with Inoperable AAC

Living with inoperable ACC can be difficult. It is important to get support from family and friends as well as from medical professionals. Additionally, lifestyle changes such a eating a healthy diet and exercising regularly can help to improve a person's outlook on life.

It is also important to keep up with regular check-ups and follow-up treatments to ensure the cancer is being monitored and managed properly. With the right course of treatment, it is possible to manage the disease and live a longer, healthier life.