Acute delayed Nausea caused by cancer chemotherapy

Acute Delayed Nausea Caused By Cancer Chemo

Cancer chemotherapy can be an unpleasant experience, not only because of the side effects of nausea and vomiting, but also because of the potential for acute delayed nausea (ADN). ADN is a type of nausea that occurs hours, days or even weeks after chemotherapy. This nausea can be difficult to manage and can significantly impair quality of life.

ADN is triggered by specific drugs used during chemotherapy, most commonly including vinca alkaloids and irinotecan. It is possible to receive the same drugs without developing ADN, however, as it is an unpredictable side effect. The frequency of acute delayed nausea in patients receiving chemotherapy depends on the specific drugs used.

The cause of ADN is unknown, but findings suggest that it is related to high emetic risk (cancer treatment-related nausea and vomiting) and/or an altered chemical composition in the gastrointestinal tract caused by the chemotherapy drugs.

Symptoms of acute delayed nausea include:

  • abdominal pain
  • nausea
  • vomiting
  • diarrhea
  • hunger
  • anxiety
  • irritability

Treatment for acute delayed nausea includes the use of medications such as antiemetics (anti-nausea medications) and anti-acids. It is important to note that some medications used to treat ADN also have potential side effects such as constipation, drowsiness, and dizziness. Therefore, it is recommended to discuss the specific medication and its potential side effects with your healthcare provider.

It is also important to note that the effects of ADN can linger and can significantly impair quality of life, leading to a cycle of nausea, anxiety, and fatigue. To prevent this, lifestyle modifications such as minimizing stress and eating small, frequent meals, can help reduce the duration and severity of symptoms. In addition, anticipatory nausea – the fear of feeling sick before chemotherapy – can be treated with behavioral therapy and even hypnosis.

With proper management and treatment, ADN can be controlled and patients can go on to enjoy an improved quality of life and an improved prognosis.