Tariquidar Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Tariquidar
Generic Tariquidar
Tariquidar Other Names Tariquidar
Formula C38H38N4O6
Weight Average: 646.744
Monoisotopic: 646.27913496
Groups Investigational
Therapeutic Class
Available Country
Last Updated: September 19, 2023 at 7:00 am


Investigated for use/treatment in ovarian cancer, lung cancer, and breast cancer.

How Tariquidar works

Tariquidar is an anthranilic acid derivative third generation P-glycoprotein (P-gp) inhibitors. P-gp is a transport protein found in normal cells that has many trasport and modulatory functions, from affecting the distribution and bioavailability of drugs to mediating the migration of dendritic cells. P-gp is responsible for multidrug resistance through transport of anti-cancer drugs out of their target cells. It is proposed that tariquidar's and its derivatives may bind to the H-binding site of P-gp through multiple mechanisms of binding.

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You find simplified version here Tariquidar

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