Lanoteplase Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Lanoteplase
Generic Lanoteplase
Lanoteplase Other Names Lanoteplase
Groups Investigational
Therapeutic Class
Available Country
Last Updated: September 19, 2023 at 7:00 am


Investigated for use/treatment in myocardial infarction.

How Lanoteplase works

Lanoteplase is a second generation derivative of alteplase, and a third generation recombinant plasminogen activator made from a deletion and point mutant of tissue type-plasminogen activator (t-PA). Lanoteplase has a longer half life than alteplase. Lanoteplase is a serine protease that binds to fibrin in a thrombus (blood clot)and cleaves the Arg-Val bond in plasminogen, producing active plasmin. Plasmin is an enzyme that degrades plasma proteins such as fibrin clots to clear blocked blood vessels that cause myocardial infarction (heart attack) or stroke.

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