Lanoteplase

Lanoteplase

Uses

Investigated for use/treatment in myocardial infarction.

How Lanoteplase works

Lanoteplase is a second generation derivative of alteplase, and a third generation recombinant plasminogen activator made from a deletion and point mutant of tissue type-plasminogen activator (t-PA). Lanoteplase has a longer half life than alteplase. Lanoteplase is a serine protease that binds to fibrin in a thrombus (blood clot)and cleaves the Arg-Val bond in plasminogen, producing active plasmin. Plasmin is an enzyme that degrades plasma proteins such as fibrin clots to clear blocked blood vessels that cause myocardial infarction (heart attack) or stroke.

Lanoteplase

Trade Name	Lanoteplase
Generic	Lanoteplase
Lanoteplase Other Names	Lanoteplase
Type
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	August 5, 2021 at 12:40 pm

Structure

Table Of contents

• Lanoteplase
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Innovators Monograph

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