Exisulind
Exisulind
Download Bissoy App to talk Doctor online
Uses
Investigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
Download Bissoy App to talk Doctor online
How Exisulind works
Exisulind is a sulindac derivative of a class of compounds called selective apoptotic anti-neoplastic drugs (SAANDs), which inhibit the enzyme cyclic guanosine monophosphodiesterase (cGMP - PDE). Exisulind is specific for apoptotic effects in precancerous and cancerous colorectal cells due to their overexpression of cGMP. Sustained elevation of cGMP and protein kinase G (PKG) activation may be also implicated in the induction of apoptosis by Exisulind.
Structure
Download Bissoy App to talk Doctor online
Download Bissoy App to talk Doctor online
Download Bissoy App to talk Doctor online
Download Bissoy App to talk Doctor online
Download Bissoy App to talk Doctor online
Download Bissoy App to talk Doctor online
Innovators Monograph
You find simplified version here Exisulind