Clenoliximab

Clenoliximab Uses, Dosage, Side Effects, Food Interaction and all others data.

Clenoliximab is a chimeric monoclonal antibody from Macaca irus against CD4 which acts as an immunomodulator. It has investigated for the treatment of rheumatoid arthritis.

Trade Name Clenoliximab
Generic Clenoliximab
Clenoliximab Other Names Clenoliximab
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Clenoliximab
Clenoliximab

Uses

Investigated for use/treatment in rheumatoid arthritis.

How Clenoliximab works

Clenoliximab is a macaque-human chimeric monoclonal antibody (immunoglobulin G4)that binds specifically to the CD4 receptor present on T-lympocytes (Helper T lymphocytes). CD-4 lymphocytes are implicated in the pathogenesis of rheumatoid arthritis (RA). Clenoliximab coats the CD4 T-lymphocytes and thus down-modulates the CD4 T-lympocytes in a dose and concentration-dependent manner without decreasing the amount of CD4 T-lympocytes in circulation.

Innovators Monograph

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