Toxoplasma gondii encephalitis

What is Toxoplasma gondii Encephalitis?

Toxoplasma gondii encephalitis (TGE) is a type of brain infection caused by Toxoplasma gondii, a type of single-celled, parasitic organism. It usually affects individuals who have weakened immune systems due to HIV/AIDS, cancer, or organ transplants. In some cases, the infection can also affect people with a healthy immune system.

Symptoms of TGE

Symptoms of TGE include:

  • Fever
  • Headache
  • Stiff neck
  • Fatigue
  • Confusion
  • Visual disturbances
  • Seizures

Diagnosis of TGE

Diagnosis of TGE may include a complete medical history and physical examination. In addition, blood tests will be done to check for Toxoplasma antibodies. A lumbar puncture may also be done to test for Toxoplasma antibody in the cerebral spinal fluid.

Treatment of TGE

The primary treatment for TGE is antiparasite medication. This typically includes medications such as pyrimethamine, folinic acid, and sulfadiazine. In some cases, antiparasitic drugs may need to be given for several weeks or months.

Conclusion

Toxoplasma gondii encephalitis is a type of brain infection caused by the Toxoplasma gondii parasite. It usually affects individuals with weakened immune systems due to HIV/AIDS, cancer, or organ transplants. Symptoms of TGE include fever, headaches, confusion, seizures, and visual disturbances. Treatment typically includes antiparasitic drugs such as pyrimethamine, folinic acid, and sulfadiazine.