Relapsed Peripheral T-Cell Lymphoma
What Is Relapsed Peripheral T-Cell Lymphoma?
Relapsed peripheral T-cell lymphoma (RPTL) is a rare type of lymphoma that starts in the white blood cells known as T-cells. It is a type of non-Hodgkin’s lymphoma, meaning it does not originate in the same lymphatic cells as Hodgkin’s lymphoma and is most common in people in their late 40s and 50s. RPTL affects the lymph nodes, spleen, and other organs, and is difficult to treat.
RPTL may be classified as indolent, aggressive, or even Very High Risk (VHR). The indolent types usually progress slowly and respond well to treatment, while aggressive types are more aggressive and prognoses tend to be more grim.
Symptoms of Relapsed Peripheral T-Cell Lymphoma
The symptoms of RPTL can vary depending on the type and stage of the cancer. Common symptoms include:
- Swollen lymph nodes, often in the neck, armpits and groin
- Unexplained weight loss
- Unexplained fever
- itching skin
- Unexplained fatigue
- Night sweats
Diagnosis and Treatment of Relapsed Peripheral T-Cell Lymphoma
The diagnosis of RPTL begins with a physical examination and a review of your medical history. Your doctor may order additional tests, such as:
- Blood tests
- Imaging tests such as CT scans and MRI scans
- Biopsy of a suspected lymph node
Treatment of RPTL depends on the type of cancer and the stage of the disease. Options include chemotherapy, radiation, targeted therapy, immunotherapy, stem cell transplant, and surgery in some cases. In advanced cases, palliative care may be needed to relieve symptoms and reduce pain.