Peritonitis caused by Aspergillus

Peritonitis caused by Aspergillus is a rare and serious type of infection of the peritoneal cavity, the protective and cushioning lining of the abdominal cavity. Aspergillus species of fungi are the most common etiology of Aspergillus peritonitis (AP). It is primarily a complication of long-term peritoneal dialysis in immunocompromised patients.

The symptoms of AP are generally non-specific and the diagnosis may be difficult to make. The signs and symptoms of AP usually include fever, abdominal pain, and abdominal mass. Other symptoms may include a tender abdomen, lower-back pain, and diarrhea. Laboratory tests may be strongly suggestive of a diagnosis of AP by demonstrating positive research studies.

The treatment of AP is mainly surgical, with removal of the affected organs or tissue whenever possible. In some cases, antifungal medications such as ketoconazole and voriconazole may be used as primary treatment, but these drugs do not always completely eliminate the infection. Antifungals are usually prescribed for long-term use and may be necessary even after surgical treatment.

To prevent the development of AP, it is important to observe good hygiene measures and to avoid activities which could allow the fungus to enter the body, such as sharing bedding or clothing. Patients with long-term peritoneal dialysis should be regularly monitored for the signs and symptoms of possible Aspergillus infection.

Prevention

Observe good hygiene measures
Avoid sharing bedding or clothing
Regular monitoring of patients with long-term peritoneal dialysis
Avoid activities which could allow the fungus to enter the body