Serotonin Syndrome

What is Serotonin Syndrome?

Serotonin Syndrome is a potentially life-threatening drug reaction that results from too much serotonin building up in the body. It is caused by an overdose of drugs that affect the body's serotonin levels, which can include antidepressants, migraine medications, and illegal drugs. Serotonin Syndrome can range from mild to severe and is most often seen when two or more drugs affecting serotonin levels are taken together.

Symptoms of Serotonin Syndrome

The most common symptoms of Serotonin Syndrome include:

  • Agitation or restlessness
  • Confusion
  • Rapid heart rate and high blood pressure
  • Diarrhea
  • Hallucinations
  • Loss of muscle coordination or twitching muscles
  • Heavy sweating
  • Headache
  • Shivering
  • Goosebumps

Treatment for Serotonin Syndrome

Treatment for Serotonin Syndrome depends on the severity of the symptoms. Mild cases may be treated with medications that reduce serotonin levels in the body and supportive care. Severe cases may require hospitalization and intensive medical monitoring and supportive treatments.

Preventing Serotonin Syndrome

The best way to prevent Serotonin Syndrome is to be sure to follow your doctor's instructions if you are taking medications that affect serotonin levels. Make sure to talk to your doctor before taking any additional medications and disclose any supplements or recreational drugs you are taking so that they can factor them into your treatment plan.