Locally Advanced Breast Cancer (LABC)

Locally Advanced Breast Cancer: Facts and Treatment

Locally advanced breast cancer (LABC) is commonly defined as an invasive form of breast cancer that remains within the breast and chest wall. It affects women of all ages but is more common in those over 40. In advanced cases, the cancer may have spread to the lymph nodes under the arm. LABC is not typically curable with surgery alone.

Most cases of LABC are to some degree resistant to chemotherapy, making treatment more difficult. Additionally, LABC often grows quickly and aggressively, making it difficult to control in some cases. It is important to understand LABC and the treatment options to ensure the best possible outcome.

Types of LABC

LABC is divided into three categories based on size and extent of the tumor.

• T1: The tumor is less than 5 cm in diameter and involves the skin. This is the least aggressive type.
• T2: The tumor is between 5 cm and 10 cm in diameter and may involve the skin. This is the most common type.
• T3: The tumor is greater than 10 cm in diameter and has grown into the chest wall and surrounding tissue. This is the most aggressive type.

Symptoms of LABC

The most common symptom of LABC is an irregular lump or swelling of the breast. Other symptoms can include changes to the size or shape of the breast, dimpling of the skin, changes to the nipple, or persistent pain or tenderness. Skin may also appear red or inflamed.

Treatment Options for LABC

Treatment for LABC will depend on the size and stage of the cancer. Treatment options may include chemotherapy, radiation, hormone therapy, and possibly surgery. The type and combination of treatments will be tailored to the individual and their specific condition.

• Chemotherapy: Chemotherapy is typically used to shrink tumors before surgery, or as an initial treatment for advanced cases.
• Radiation: Radiation helps to kill cancer cells and is often used after surgery or chemo to ensure cancer cells are destroyed.
• Hormone therapy: Hormone therapy may be used in some cases to help reduce the risk of LABC returning.
• Surgery: Surgery is usually used to remove any remaining tumors. It may also be used to restore the appearance of the breast.

It is important to follow the treatment plan outlined by your doctor and seek out support and resources to help manage your condition. With proper management, LABC can be effectively treated and managed.