Metastatic Basal cell carcinoma
What is Metastatic Basal Cell Carcinoma?
Metastatic Basal Cell Carcinoma (mBCC) is an aggressive form of skin cancer. It starts in the cells that make up the outer layer of the skin (the basal layer). mBCC is a rare form of skin cancer that has a tendency to spread (metastasize) to other parts of the body.
Risk Factors of Metastatic Basal Cell Carcinoma
The exact cause of mBCC is unknown, although certain factors have been identified that can increase the risk of developing this condition:
- Fair skin and light-colored eyes
- Chronic sun exposure or tanning bed use
- Family history of skin cancer
- Immuno-suppressive drugs or treatments
Signs and Symptoms of Metastatic Basal Cell Carcinoma
The signs and symptoms of mBCC can vary depending on the location and extent of the cancer. Signs may include:
- Skin discoloration in the area where the cancer originated
- Pigmented patches, lesions, or bumps on the skin
- Painful or itchy skin
- Unexplained bleeding or discharge from the site of the cancer
- Unusual lumps or bumps
If the cancer has already spread to other parts of the body, additional symptoms may include:
- Pain in the affected area
- Fever
- Fatigue
- Lymph node swelling
- Weight loss
Diagnosis of Metastatic Basal Cell Carcinoma
mBCC is typically diagnosed with a biopsy of the affected area, in which the doctor removes a sample of the cancerous tissue and examines it under a microscope. Depending on the location and extent of the cancer, other tests may also be necessary for diagnosis, including CT scans, MRI's, and ultrasound.
Treatment of Metastatic Basal Cell Carcinoma
Treatment of mBCC can involve surgery, radiation therapy, chemotherapy, biological therapy, or a combination of treatments. Surgery is often the first line of treatment and may be used to remove not only the cancerous cells, but also some surrounding healthy tissue. Radiation therapy is another option and may be used to shrink or destroy the cancerous cells. Chemotherapy and biological therapy may be used to slow the growth of the cancer and reduce the spread to other parts of the body.
Conclusion
Metastatic Basal Cell Carcinoma (mBCC) is an aggressive form of skin cancer that can spread to other parts of the body. Early diagnosis and treatment are important for improving the chances of a successful outcome, so seek medical attention immediately if you notice any abnormal changes in your skin.