Locally recurrent radioactive iodine-refractory Thyroid cancer
Understanding Locally Recurrent Thyroid Cancer
A type of thyroid cancer that is locally recurrent is radioactive iodine-refractory thyroid cancer, or RRTC. This cancer has been identified as more aggressive and has been theorized by some researchers as a separate entity within the class of advanced thyroid cancers, with its own prognosis and needs for management.
It occurs in the thyroid gland following previous treatments for thyroid cancer, such as a thyroidectomy, radiation therapy, or combination of both. In addition, some cases of RRTC may not have any known prior treatments for thyroid cancer.
Symptoms of RRTC
Symptoms for RRTC may vary and depend on the location and size of the tumor and whether there are any metastases. One of the main symptoms of this type of cancer is a nodule or swelling in the neck. Other common symptoms may include:
- Pain or discomfort in the throat or neck
- Feelings of fullness in the neck
- Difficulty breathing or swallowing
- Hoarseness of the voice
- Cough, shortness of breath, or wheezing
- Fever or night sweats
- Weight loss
- Fatigue
Diagnosis and Treatment of RRTC
Upon diagnosis of RRTC, treatment may include a combination of surgery, radiation therapy, chemotherapy, hormone treatment, or a combination of these. Surgery is often the primary treatment for RRTC and involves the removal of the tumor or growth(s). Radiation therapy may be used to target residual cancer cells found after surgery, while chemotherapy may be effective for controlling the spread of the cancer. Hormone therapy may be used as well, to target cancer cells that may be more sensitive to hormones.
Follow-up care is important for people who have had RRTC, and may include imaging tests and appointment with a specialist to monitor for any recurrence. It is important to speak with a cancer care team to determine the best treatment plan for each person.