Quantitative Bence-Jones protein test

Quantitative Bence-Jones Protein Test

The Quantitative Bence-Jones Protein Test is a lab procedure used to detect and measure the concentration of monoclonal immunoglobulin (mIg) in serum or urine samples. This type of immunoglobulin is found in conditions such as multiple myeloma and other benign and malignant conditions. The Quantitative Bence-Jones Protein Test is an important step in diagnosing and monitoring the progression of these conditions.

Preparation

The sample to be tested is usually prepared by a health care professional. Samples can include both serum and urine. The sample should be taken correctly to ensure accurate results. The sample should also be placed in a sterile, labeled container and kept in a cool place until it is ready to be tested.

Procedure

In the Quantitative Bence-Jones Protein Test, a lab technician will use a spectrophotometer to measure the amount of IgG in the sample. The IgG is then measured in relation to the serum albumin or urea in the sample. The results are then used to determine the concentration of mIg in the sample.

Types of Quantitative Bence-Jones Protein Test

There are two types of Quantitative Bence-Jones Protein Test. One type involves measuring the total amounts of mIg in the sample. The other type involves measuring only the light chains in the sample.

Risks

The Quantitative Bence-Jones Protein Test is generally safe and doesn't pose any risks to the patient. However, it should only be performed by trained and certified medical professionals.

Why the Test is Performed

The Quantitative Bence-Jones Protein Test is performed to detect and measure the abundance of mIg in the bloodstream or urine. This gives doctors an indication of the presence or absence of various myeloma and other conditions. It also helps them to monitor the progression of such diseases and to adjust treatment plans accordingly.

When the Test is Performed

The Quantitative Bence-Jones Protein Test is usually performed when a patient is suspected to be suffering from multiple myeloma or related diseases. It is also used to monitor the progression of such diseases and to assess the effectiveness of treatment.