Mononucleosis spot test

Mononucleosis Spot Test

The Mononucleosis Spot Test, also called the Rapid Spot Mononucleosis Test, refers to a blood test that looks for antibodies that are associated with an Epstein-Barr virus (EBV) infection, also commonly known as Mono. This test helps to distinguish Mono from other viral infections that may cause similar symptoms.


No preparation is needed for the Mononucleosis Spot Test. You don’t have to fast or stop taking your medications before this test.


The Mononucleosis Spot Test is a simple, easy procedure. A healthcare worker will take a blood sample from a vein in your arm with a needle. The sample is then sent to a lab for analysis for the presence of antibodies to EBV.


There are two types of Mononucleosis Spot Test that can be performed to determine a diagnosis of Mono. The first is a rapid mononucleosis spot test, which can give results within an hour. The second is an immunofluorescence assay (IFA), which takes a few days to produce results.


The Mononucleosis Spot Test is considered relatively safe. However, as with any medical procedure, there are some potential risks associated with this test including infection, bruising, and discomfort at the injection site. Additionally, false positive or false negative results may occur as well.

Why is Mononucleosis Spot Test Done?

The Mononucleosis Spot Test is used to diagnose a mono infection. It is typically ordered when a patient has symptoms including fever, sore throat, swollen lymph nodes, and extreme fatigue. The test can also be ordered to rule out a mono infection when other diseases with similar symptoms are being considered.

When to Get Tested?

It is recommended to get tested for Mono if you are experiencing any of the symptoms associated with the virus. You should also get tested if you have been exposed to someone with Mono or may have contracted the virus through sexual contact.

What Do the Results Mean?

The results of the Mononucleosis Spot Test can tell if you have an active EBV infection or if you have had a past EBV infection and are now recovered. Positive results indicate that you have an active EBV infection and should begin treatment. Negative results can indicate that you have had a past EBV infection and are now recovered, or that you do not have an active EBV infection.