Small Lymphocytic Lymphoma

What is Small Lymphocytic Lymphoma?

Small Lymphocytic Lymphoma (SLL) is a rare type of non-Hodgkin lymphoma, which is a type of blood cancer that affects the white blood cells known as B lymphocytes. It is a type of low-grade B-cell lymphoma and is known for its slow-growing nature.

SLL specifically affects the B lymphocytes, which are part of the immune system, as they grow abnormally and form tumors. This cancer typically affects areas such as the lymph nodes, bone marrow, and spleen.

Signs and Symptoms of Small Lymphocytic Lymphoma

SLL is so slow-growing that it can be difficult to detect, as many of the symptoms can be confused with those of other illnesses, such as the common cold or flu. Common symptoms of SLL may include:

  • Fever
  • Fatigue
  • Night sweats
  • Weight loss
  • Loss of appetite
  • Swollen lymph nodes, usually in the neck, armpit, and groin
  • Enlarged liver and/or spleen

Causes of Small Lymphocytic Lymphoma

The exact cause of SLL is not known, but experts believe that various genetic, environmental, and lifestyle factors can increase a person’s risk of developing the condition. These factors may include:

  • Being exposed to certain chemicals or chemicals such as benzene
  • Having a weakened immune system due to certain medical conditions or medications
  • Being a current or former smoker
  • Being over the age of 65

Diagnosis of Small Lymphocytic Lymphoma

A diagnosis of SLL is typically made after the doctor performs a physical exam, looks at the person's medical history, and runs a series of tests. These tests may include blood tests, imaging tests such as X-rays and CT scans, bone marrow biopsy, and lymph node biopsy.

Treatment of Small Lymphocytic Lymphoma

The treatment of SLL depends on the severity of the condition and the person’s overall health. Treatments may include chemotherapy, radiation therapy, targeted therapy, immunotherapy, and stem cell transplant. In some cases, the doctor may recommend watching and waiting instead of starting treatment right away.

Complications of Small Lymphocytic Lymphoma

If left untreated, SLL can cause complications such as anemia, infections, and organ damage. It is important to speak to a doctor if you have any of the symptoms of SLL mentioned above, as early diagnosis and treatment can help improve the prognosis and reduce the risk of complications.