Refractory Diffuse Large B Cell Lymphoma
What is Refractory Diffuse Large B Cell Lymphoma?
Refractory Diffuse Large B Cell Lymphoma is a type of non-Hodgkin lymphoma (NHL) that is a very aggressive form of blood cancer. It is an advanced form of NHL and is typically found in the later stages of this type of cancer. The disease is associated with a high mortality rate and is difficult to treat, making it particularly difficult to manage.
Signs and Symptoms of Refractory Diffuse Large B Cell Lymphoma
The symptoms of refractory diffuse large B cell lymphoma vary depending on the individual and their stage of illness. Generally, however, the signs and symptoms of this form of NHL can include:
- Swollen lymph nodes in the neck, armpits, or groin
- Fever
- Persistent fatigue
- Night sweats
- Unexplained weight loss
- Itching
- Unexplained bruises or bleeding
- Lack of appetite
- Pain in the abdomen
Diagnosis of Refractory Diffuse Large B Cell Lymphoma
If you are showing any of these symptoms of refractory diffuse large B cell lymphoma, it is important to seek medical attention from a primary care professional or specialist. The diagnosis of this type of NHL typically requires the following:
- Physical examination to identify swollen lymph nodes
- Blood tests to evaluate the levels of red and white blood cells
- Imaging tests such as CT scans, MRI scans, and PET scans to help evaluate the extent of the lymphoma in the body
- Biopsy of the lymph nodes and other affected tissues to analyze the structure of the cells and help to determine the type of lymphoma.
Treatment for Refractory Diffuse Large B Cell Lymphoma
Treatment for refractory diffuse large B cell lymphoma may include chemotherapy, radiation therapy, and surgery. In some cases, stem cell transplants may also be used to help keep the disease in remission. In general, the goal of treatment is to keep the cancer in remission for as long as possible.
For those with refractory diffuse large B cell lymphoma, it is important to work with a team of specialists to determine the best plan of care. In cases where the cancer is not responding to standard treatments, your doctor may suggest additional treatments such as targeted therapies or clinical trials.