Poisoning by parasympathomimetics (cholinergics)

Poisoning by Parasympathomimetics (Cholinergics)

Poisoning by parasympathomimetics (also known as cholinergics or anticholinergics) is caused by substances that stimulate the parasympathetic nervous system. Symptoms can range from mild to severe, depending on the amount and type of substance ingested. Confusion, disorientation, rapid heart rate, muscle cramps, fever, respiratory failure, seizures, and coma are some of the more severe symptoms of parasympathomimetic poisoning.

Common sources of parasympathomimetic poisoning include pesticides, household cleaners, and some prescription and over-the-counter medications. Inhaling, touching, or ingesting any of these substances can lead to exposure. In some cases, exposure may be accidental, but in other cases, it may be intentional overdose.

Treatments for parasympathomimetic poisoning vary depending on the severity of the exposure. Depending on the severity of the case, treatment may involve determining the concentration of the substance in the blood and administering an anticholinergic medication such as atropine. In some cases, a ventilator may be necessary to help the patient breathe. In some cases, dialysis may be necessary to remove the poison from the patient’s body.

In order to prevent parasympathomimetic poisoning, people should be aware of the risks associated with certain products. People should read the labels of any products they are using and take extra caution with products that contain anticholinergic or parasympathomimetic ingredients. People should also avoid leaving cleaning products, pesticides, and other potentially dangerous products unsecured. Lastly, people should discard unused or expired medications as soon as possible.

Tips to Prevent Parasympathomimetic Poisoning:

• Read product labels and take extra caution with products that contain anticholinergic or parasympathomimetic ingredients.
• Secure products that may contain hazardous ingredients.
• Keep all hazardous products, such as pesticides, out of the reach of children.
• Discard unused or expired medications as soon as possible.
• Consider consulting a toxicologist or pharmacist if unsure about the safety of a product.