Non-Small Cell Lung Carcinoma (NSCLC)

Non-small cell lung carcinoma (NSCLC) is one of the most common and aggressive forms of lung cancer. This type of cancer affects the cells of the lungs and can affect both the outer layer of the lungs (called the pleura) as well as the inner lining of the lungs (the alveoli). NSCLC is divided into three subtypes— adenocarcinoma, squamous cell carcinoma, and large cell carcinoma— based on the size and shape of the cells.

NSCLC is usually caused by smoking, but it can also be caused by other environmental factors such as asbestos, air pollution, and radiation. The symptoms of NSCLC may vary depending on the type and stage of the cancer, but they may include a persistent cough, chest pain, shortness of breath, fatigue, and weight loss.

Treatment for NSCLC depends on the type and stage of the cancer, but it generally includes surgery, chemotherapy, radiation therapy, or immunotherapy. For some people, a combination of these treatments may be recommended. The goal of treatment is to reduce the size of the tumor and prevent it from spreading to other parts of the body. In some cases, the cancer may be cured.

Research into new treatments for NSCLC is ongoing, and new treatments are being developed and tested all the time. These treatments include targeted therapies, which focus on specific changes in the cancer cells, and immunotherapy, which uses the body’s own immune system to fight the cancer.

It is important for anyone with NSCLC to receive regular medical care, as early detection is key to survival. Talk to your doctor about your risk factors and any signs or symptoms you may have.

Main Risk Factors

Smoking cigarettes or other forms of tobacco
Occupational exposure to substances such as asbestos, radon, diesel exhaust, and other carcinogens
Air pollution
Family history of lung cancer