Moderate to Severe Plaque Psoriasis

What is Moderate to Severe Plaque Psoriasis?

Moderate to Severe Plaque Psoriasis is a chronic skin condition that causes inflammation, redness, and scaling on the skin. Plaque psoriasis is the most common form of the disease, affecting up to 80 percent of people with psoriasis. It is characterized by red patches on the skin, covered with silvery-white scales, which can be itchy and painful.

What are the Symptoms of Moderate to Severe Plaque Psoriasis?

The most common symptoms of moderate to severe plaque psoriasis include:

• Red patches on the skin, covered with silvery-white scales
• Pain, itching, inflammation, and burning sensation in the affected area
• Thick, dry, cracked skin that may bleed
• Fingernails and toenails that are pitted, discolored, and may separate from the nailbed
• Joint pain and swelling, especially in the fingers and toes

What Causes Moderate to Severe Plaque Psoriasis?

The exact cause of moderate to severe plaque psoriasis is unknown, but it is believed to be related to the immune system, genetics, and environmental triggers such as stress, infection, or certain medications. People with a family history of psoriasis are more likely to develop the condition.

How is Moderate to Severe Plaque Psoriasis Treated?

Moderate to severe plaque psoriasis can be treated with a variety of treatments, including topical medications, oral medications, and light therapy. Topical treatments include corticosteroids, vitamin D analogues, retinoids, salicylic acid, and coal tar. Oral medications include methotrexate, cyclosporine, biologic therapies, and systemic corticosteroids. Light therapy can be used in combination with topical or oral treatments to improve psoriasis symptoms.

Complications of Moderate to Severe Plaque Psoriasis

People with moderate to severe plaque psoriasis may be at an increased risk of developing certain complications, including:

• Skin infections
• Eye inflammation
• Joint problems, including psoriatic arthritis
• Depression and anxiety
• Increased risk of cardiovascular disease