Metastatic Transitional Cell Carcinoma of the Urothelial Tract

Metastatic Transitional Cell Carcinoma of the Urothelial Tract: What You Need to Know

Metastatic transitional cell carcinoma of the urothelial tract is the most common type of bladder cancer. It can spread to other parts of the body, including the bladder, prostate, and walls of the urinary tract. This cancer can also spread to other nearby organs and tissues. It is important to know the signs and symptoms of this cancer so you can get timely treatment.

What Causes Metastatic Transitional Cell Carcinoma of the Urothelial Tract?

Most often, transitional cell carcinoma of the urothelial tract is caused by smoking. Exposure to certain industrial chemicals, such as those used in the rubber industry, can also increase the risk of this cancer. Some people can have an increased risk due to family history, radiation therapy, and chronic infections. Taking immunosuppressant drugs after an organ transplant can also increase the risk.

Signs and Symptoms of Metastatic Transitional Cell Carcinoma of the Urothelial Tract

When the cancer cells metastasize onto other organs, it can cause a wide range of symptoms. The most common symptoms include:

  • Pain in the lower abdomen and back
  • Frequent urge to urinate
  • Blood in the urine
  • Fever and chills
  • Fatigue
  • Unexplained weight loss
  • Nausea and vomiting

Diagnosis and Treatment

Diagnosing metastatic transitional cell carcinoma of the urothelial tract requires various tests, including an imaging scan, biopsy, and urine tests. Depending on the stage of the cancer, treatment may involve surgery, radiation, chemotherapy, or targeted therapies. Immunotherapy is also an option for people with advanced stages of this cancer.

The Outlook

The outlook for metastatic transitional cell carcinoma of the urothelial tract depends on how far the cancer has spread as well as the patient's age and overall health. Early diagnosis and treatment can help increase the chances of successful treatment. Some people with major organ involvement may be given palliative care to manage symptoms.