Intrahepatic
What is Intrahepatic Cholestasis?
Intrahepatic cholestasis is a disorder of the liver in which bile cannot flow properly from the liver into the intestines. It is also known as obstetric cholestasis, recurrent jaundice, and IC. Intrahepatic cholestasis can occur in pregnant women, infants, and people of any age who have other biliary tract diseases or issues. Intrahepatic cholestasis is a serious condition that can lead to a wide range of complications, including liver damage and scarring, miscarriage, preterm labor, and increased risk of stillbirth.
Symptoms of Intrahepatic Cholestasis
The most common symptom of intrahepatic cholestasis is itching, which can be severe. The itching is usually concentrated in the hands and feet. Other symptoms can include dark urine, light-colored stools, jaundice, fatigue, and nausea. Some cases of intrahepatic cholestasis can also be associated with liver disease.
Diagnosing Intrahepatic Cholestasis
Intrahepatic cholestasis is diagnosed with a combination of physical exam, laboratory tests, and imaging studies. Blood tests can be used to detect any abnormalities in the liver and bile ducts. Ultrasound, MRI, and CT scans can be used to look for any blockages in the bile ducts. A liver biopsy may also be necessary to determine the severity of the condition and the exact cause.
Treatment of Intrahepatic Cholestasis
The goals of treatment for intrahepatic cholestasis depend on the underlying cause. In some cases, treatment may involve medications to reduce symptoms. These may include drugs to reduce itchiness, antibiotics to help prevent infections, and medications to reduce bile production. In severe cases, treatment may include surgery to remove any blockages in the bile ducts or to address any other underlying cause. Dietary changes, such as avoiding certain foods that can irritate the liver, may also be recommended.
Risks of Intrahepatic Cholestasis
Intrahepatic cholestasis can lead to a number of complications, including liver failure, kidney problems, and increased risk of preterm labor and miscarriages. It can also lead to jaundice, which can cause vision problems and brain damage in infants. Intrahepatic cholestasis can increase the risk of cancer in some people.
Preventing Intrahepatic Cholestasis
Intrahepatic cholestasis can be prevented by treating any underlying conditions as soon as possible. People at risk should be tested for any liver or biliary system disorders. Eating a healthy diet and avoiding certain foods, such as alcohol, that can irritate the liver can also help to reduce the risk of developing the condition.
Living with Intrahepatic Cholestasis
For those living with intrahepatic cholestasis, it is important to follow all treatment recommendations. It is also important to pay close attention to any changes in symptoms and to address them with a doctor right away. People with the condition should be aware of any potential complications and should be monitored closely by their doctor.
Coping with Intrahepatic Cholestasis
Living with intrahepatic cholestasis can be challenging, and many people may struggle with feelings of fear and anxiety. It is important to take the time to talk with a doctor or counsellor who can help with any emotional struggles. Doing activities that make you feel relaxed, such as yoga, meditation, or tai chi, can also help you cope with the condition.
Key Points
- Intrahepatic cholestasis is a disorder of the liver where bile cannot flow properly.
- The most common symptom of intrahepatic cholestasis is itching, which can be severe.
- Intrahepatic cholestasis can be diagnosed with a combination of physical exam, laboratory tests, and imaging studies.
- Treatment for intrahepatic cholestasis often involves medications, dietary changes, and, in severe cases, surgery.
- Intrahepatic cholestasis can lead to a number of complications, including liver failure and increased risk of preterm labor and miscarriages.
- Intrahepatic cholestasis can be prevented by treating any underlying conditions and avoiding certain foods that can irritate the liver.
- Living with intrahepatic cholestasis can be challenging, and it is important to take the time to manage any emotional struggles.