Hyperthyroidism caused by Amiodarone

Hyperthyroidism Caused by Amiodarone

Hyperthyroidism is a disorder caused by an overactive thyroid gland, which can lead to the production of too much thyroid hormone. It is typically found in patients who take certain medications, such as amiodarone, for certain heart conditions. Amiodarone is a medication used to treat abnormal heart rhythms, and its use can lead to excessive thyroid hormone production, which can then result in hyperthyroidism.

The side effects of amiodarone on the thyroid can be varied, but the most common symptom of amiodarone-induced hyperthyroidism is an increased heart rate and palpitations. Additional side effects can include nervousness, sweating, weight loss, diarrhea, and insomnia.

The diagnosis of amiodarone-induced hyperthyroidism is typically made through a combination of physical exam, laboratory tests, and imaging studies. Physical exam findings may include a rapid heart rate, goiter, or cachexia. Laboratory tests may include thyroid function tests, urine tests, and imaging studies, such as a nuclear scan or ultrasound of the thyroid.

Treatment of Amiodarone Induced Hyperthyroidism

The treatment of amiodarone-related hyperthyroidism is typically the same as it is for other forms of the condition. The goal is to restore the balance of hormones in the body.

The most common treatment for this condition is antithyroid medication, which is used to suppress the thyroid gland and reduce thyroid hormone production. In addition, beta-blockers may be used to control the rapid heart rate associated with this condition.

In some cases, amiodarone may need to be stopped in order to control the effects of hyperthyroidism. Stopping amiodarone can be extremely difficult, and some patients may require a gradual tapering off of the medication. Additionally, surgical removal of the thyroid may be necessary in cases of severe hyperthyroidism.


Amiodarone can cause hyperthyroidism due to excessive thyroid hormone production. The symptoms of this condition include rapid heart rate, sweating, weight loss, and nervousness. Diagnosis is typically made through a combination of physical exam, laboratory tests, and imaging studies. Treatment of amiodarone-induced hyperthyroidism typically includes antithyroid medication, beta-blockers, and in some cases stopping or tapering amiodarone, or surgery to remove the thyroid.