Hemorrhagic cystitis caused by cyclophosphamide

What is Hemorrhagic Cystitis?

Hemorrhagic cystitis is a serious medical condition characterized by inflammation and bleeding of the bladder. It is usually caused by a virus, but it can also be linked to certain drugs, such as cyclophosphamide.

What is Cyclophosphamide?

Cyclophosphamide is an antineoplastic medication used to treat a variety of cancer and non-cancer conditions. It is a chemotherapeutic drug that interferes with the growth and division of cancer cells.

How does Cyclophosphamide cause Hemorrhagic Cystitis?

Cyclophosphamide has the potential to cause diffuse injury to the mucosa of the bladder. This injury can lead to inflammation, bleeding, and other signs and symptoms of hemorrhagic cystitis.

Symptoms of Hemorrhagic Cystitis

  • Hematuria (blood in urine)
  • Pain with urination
  • Frequent urination
  • Fever
  • Abdominal pain
  • Fatigue

Diagnosing and Treating Hemorrhagic Cystitis

If you suspect hemorrhagic cystitis, your doctor may order tests to confirm the diagnosis and rule out other conditions. Treatment will depend on the underlying cause of the cystitis, but generally involves rest, fluids, and medications to reduce inflammation and pain.

Conclusion

Hemorrhagic cystitis is an uncommon but serious side effect of cyclophosphamide. It is important to recognize the symptoms of hemorrhagic cystitis, so treatment can be started quickly. Talk to your doctor about the risks and benefits of taking cyclophosphamide, and be sure to report any changes in urinary health.