Granuloma Inguinale


What is Granuloma Inguinale?

Granuloma inguinale, sometimes referred to as donovanosis, is a bacterial infection caused by Klebsiella granulomatis or related species. It is most common in tropical and subtropical regions and is sexually transmitted. Symptoms typically develop two to nine weeks after exposure to an infected partner and include a painless, red-brown ulcer near the genitals.


Symptoms of granuloma inguinale may include:

  • Painful ulcers on the genitals and nearby areas such as the thighs or groin.
  • A red or purple smooth-edged ulcer or surface patch.
  • Lymph node enlargement near the injury, which may be discolored or purplish.
  • Itching, pus, and swelling near the ulcer.


Granuloma inguinale may be diagnosed by its physical symptoms. To confirm the diagnosis, a sample of the tissue near the ulcer may be taken for microscopic examination and culture. If the tissues contain the bacteria, a diagnosis of granuloma inguinale may be confirmed.


The treatment for granuloma inguinale usually involves the use of antibiotic drugs, such as doxycycline or erythromycin. The antibiotics must be taken for at least seven days to ensure that all of the bacteria are eradicated.


To prevent the spread of granuloma inguinale, practice safe sex, such as the use of condoms, and avoid contact with anyone who has active or healing lesions. If left untreated, the infection can spread and cause serious problems, such as scarring or complications with fertility.