Methyltar Od

Methyltar Od Tablet

Methyltar Od is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Uses

Methyltar Od is used for-

  • Peripheral Neuropathies
  • Diabetic Neuropathy
  • Verteberal Syndrome
  • Nerve Compression Syndrome
  • Multiple sclerosis
  • Amyotrophic lateral sclerosis
  • Parkinson’s disease
  • Alzheimer’s disease
  • Diabetic retinopathy
  • Entrapment neuropathy
  • Drug induced neuropathy
  • Megaloblastic anemia due to Vitamin B12 deficiency

Methyltar Od is also used to associated treatment for these conditions: Vitamin B12 Deficiency, Nutritional supplementation

Methyltar Od

Trade Name Methyltar Od
Generic Mecobalamin
Mecobalamin Other Names Co-methylcobalamin, MeCbl, Mecobalamin, Mecobalamina, Mecobalaminum, Methyl vitamin B12, Methyl(III)cobalamin, Methylcobalamin
Type Tablet
Formula C63H91CoN13O14P
Weight Average: 1344.3823
Monoisotopic: 1343.587806391
Therapeutic Class Drugs for Megaloblastic Anemia
Manufacturer Nectar Lifesciences Ltd
Available Country India
Last Updated: June 23, 2021 at 9:00 am

Structure

Methyltar Od
Mecobalamin Structure

Dosage

Methyltar Od dosage

Tablet: The usual adult dosage is one 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. 

Injection:

  • Peripheral neuropathies: The usual adult dosage is one ampoule equivalent to 500 mcg of Methyltar Od, administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
  • Megaloblastic anemia: The usual adult dosage is one ampoule equivalent to 500 mcg of Methyltar Od, administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Methyltar Od every one to three months as maintenance therapy

Side Effects

Generally Methyltar Od is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Methyltar Od.

Precaution

The medicine should not be used for months if there is no response at all after its use for a certain period of time.

Interaction

Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.

Food Interaction

No interactions found.

Pregnancy & Breastfeeding use

Not recommended during pregnancy & lactation.

Contraindication

Hypersensitivity to any component of this product.

Special Warning

Use in children: Not recommended.

Storage Condition

Oral: Store at room temperature. Protect from moisture and light.

Parenteral: Store at room temperature. Do not expose to direct light.

Innovators Monograph

Methyltar Od contains Mecobalamin see full prescribing information from innovator // generic/mecobalamin/mecobalamin-injection-prescribing-information" Monograph