ACTH blood test

ACTH Blood Test: Overview

The adrenocorticotropic hormone (ACTH) blood test is used to diagnose the cause of Cushing's syndrome. Cushing's syndrome is a hormonal disorder caused by excess cortisol in the body. This test measures the level of ACTH, a hormone released by the pituitary gland. An ACTH blood test is also used to diagnose problems with the hypothalamus or pituitary gland.

Preparation for ACTH Test

No preparation is needed for the ACTH test. You can eat and drink as usual. However, tell your doctor if you are taking any medicines. Some medicines, such as corticosteroids, may affect the results of the test.

Procedure for ACTH Test

The ACTH test is a simple procedure. It is performed at a hospital or clinic. A health care provider draws a sample of blood from a vein in your arm. The sample will be sent to a laboratory for analysis. You may experience some pain or discomfort during the procedure.

Types of ACTH Test

  • ACTH Stimulation Test – This test is used to diagnose the cause of Cushing's syndrome. It involves the injection of a synthetic form of ACTH and measuring the cortisol level after one hour.
  • ACTH Suppression Test – This test is used to diagnose pituitary tumors. It involves the injection of a drug that suppresses ACTH and measuring the cortisol level after one hour.

Risks of ACTH Test

The ACTH test is generally considered safe. However, there is a risk of dizziness, lightheadedness, or fainting from becoming too relaxed after the injection of the drug. In rare cases, an allergic reaction to the drug can occur.

Why ACTH Blood Test is Done?

The ACTH test is used to diagnose Cushing's syndrome, a hormonal disorder caused by excess cortisol. It is also used to distinguish the cause of Cushing's syndrome, evaluate the response to treatment, monitor adrenal function, and diagnose pituitary tumors.

When is ACTH Test Recommended?

ACTH tests are recommended if your doctor suspects you may have Cushing's syndrome. It is also recommended to diagnose adrenal insufficiency and to monitor adrenal function in people with chronic illnesses such as HIV and certain types of cancer.