Still's Disease
What Is Still's Disease?
Still's disease, also known as systemic-onset juvenile idiopathic arthritis (JIA), is an inflammatory disorder of unknown cause that affects many joints and organs in the body. It usually begins in childhood or adolescence and affects adolescents and adults, mainly ages 5-40. It's rare in children younger than 5, and occurs more often in girls than boys. The disorder is named after George F. Still, an English doctor who described it in the first decade of the 20th century.
Symptoms of Still’s Disease
The most common symptoms of Still’s disease include:
- Fever
- Joint pain, swelling and stiffness
- Rash
- Enlargement of the lymph nodes
- Enlargement of the spleen
- Fatigue
- Weight loss
- Muscle pain
Causes of Still’s Disease
The exact cause of Still's disease is unknown, but it is believed to be an autoimmune disorder. It has been linked to a genetic factor, and many cases of Still's disease occur in families with a history of the disorder. It may also be caused by a virus or bacteria, but this has not been proven.
Treatment for Still’s Disease
Treatment for Still's disease typically includes medications to relieve pain and inflammation, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. Disease-modifying anti-rheumatic drugs (DMARDs) may also be used. In serious cases, aggressive therapy with drugs that suppress the immune system may be necessary. In some cases, physical therapy and exercise may be beneficial.