Salicylate poisoning

What is Salicylate Poisoning?

Salicylate poisoning, also known as aspirin poisoning, is an intoxication caused by excessive use of products containing salicylic acid or its derivatives. The substances most commonly involved are aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs). Salicylates can be found in both prescription and over-the-counter drugs, dietary supplements, herbals, and other plant-based products.

Signs and Symptoms of Salicylate Poisoning

Signs and symptoms of salicylate poisoning can vary and can range from mild to severe. Common signs and symptoms may include:

  • Respiratory difficulty (e.g., rapid breathing, wheezing, shortness of breath)
  • Fever
  • Dehydration
  • Nausea and vomiting
  • Flushing (reddening of the skin)
  • Confusion
  • Agitation
  • Dizziness and lightheadedness

Treatment

Treatment for salicylate poisoning typically involves supportive care, such as providing fluids, monitoring vital signs, maintaining proper oxygenation, and ensuring proper nutrition. Depending on the severity of the poisoning, more aggressive treatment may be necessary, such as dialysis or charcoal hemoperfusion. In cases of severe poisoning, hospitalization may be required.

Prevention

The best way to prevent salicylate poisoning is to take medications only as prescribed and avoid taking any more than the recommended dose. If you are taking over-the-counter medications, it’s important to read labels carefully to make sure you are not taking more than the recommended dose. It’s also important to be aware of the risks of mixing medications, as taking more than one medication that contains salicylates can increase the risk of poisoning.