Non-Hodgkin's Lymphoma (NHL)
What is Non-Hodgkin's Lymphoma (NHL)?
Non-Hodgkin's lymphoma (NHL) is a type of cancer that affects the lymphatic system, which is part of the body's immune system. NHL can originate from any part of the body that contains lymphoid tissue, including the lymph nodes, spleen, bone marrow, and more. It occurs when certain white blood cells, called lymphocytes, grow and divide out of control.
Types of Non-Hodgkin's Lymphoma (NHL)
There are many different types of NHL. Some of the most common types include:
- Diffuse large B-cell lymphoma (DLBCL). This type of NHL first develops in B-cells, which are a type of white blood cell that helps fight infections.
- Follicular lymphoma (FL). This type of NHL develops in follicular lymphoma cells, which are B-cells that have a specific protein marker called follicular lymphoma antigen (FLC).
- Marginal zone lymphoma (MZL). This type of NHL develops in marginal zone B-cells, which are found in the outer edges of lymphoid tissues.
- Chronic lymphocytic leukemia (CLL). This type of NHL develops in B-cells in the bone marrow.
Symptoms of Non-Hodgkin's Lymphoma (NHL)
The symptoms of NHL vary depending on the type of NHL and where it is located in the body, but some of the most common symptoms include:
- Swollen lymph nodes in the neck, armpits, or groin
- Fever
- Weight loss
- Night sweats
- Fatigue
- Pain in the abdomen or chest
- Coughing or difficulty breathing
Diagnosis and Treatment of Non-Hodgkin's Lymphoma (NHL)
NHL is diagnosed with imaging tests, blood tests, and tissue samples. Treatment for NHL may include chemotherapy, radiation therapy, targeted therapy, stem cell transplants, or surgery. The type of treatment depends on the type and stage of the cancer, as well as the overall health of the patient.