Ovarian Function Insufficiency

Ovarian Function Insufficiency

Ovarian Function Insufficiency is a condition in which the ovaries are no longer producing the hormones needed to support a healthy reproductive system. It can cause fertility issues, irregular menstrual cycles, and other complications. While it is not always curable, there are various treatments available to help manage symptoms and improve overall health.

Causes of Ovarian Function Insufficiency

The most common cause of ovarian insufficiency is genetic mutations, which can affect the way the ovaries develop and function. Other causes can include high body weight, chronic use of certain medications, and exposure to environmental toxins. In some cases, the cause of ovarian insufficiency can be unknown.

Symptoms of Ovarian Function Insufficiency

  • Painful periods
  • Menstrual irregularities
  • Hot flashes
  • Night sweats
  • Fatigue
  • Dry skin
  • Depression
  • Reduced libido
  • Infertility


A diagnosis of ovarian insufficiency is typically made based on a patient’s history and physical examination, as well as through a blood test. A blood test can measure levels of follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), and hormones known as androgens. An ultrasound may also be used to evaluate the ovaries.


Treatments for ovarian insufficiency depend on the underlying cause and the severity of symptoms. Hormonal contraception may be used to regulate menstrual cycles, while medications can help reduce the symptoms of hot flashes and night sweats. For women of childbearing age, in vitro fertilization (IVF) or other assisted reproductive technologies may be used to treat infertility. Surgery may be necessary to remove ovarian cysts or tumors.


To help reduce the risk of ovarian insufficiency, certain preventative measures can be taken. Maintaining a healthy weight, practicing safe sex, and avoiding environmental toxins can help minimize the risk. If a woman has been prescribed medication for a medical condition, it’s important to discuss any potential risks of ovarian insufficiency before beginning treatment.