Mucocutaneous Lymph Node Syndrome

What is Mucocutaneous Lymph Node Syndrome?

Mucocutaneous Lymph Node Syndrome (MLNS), is a rare, autoimmune disorder that affects the skin and mucous membranes. The syndrome is characterized by intense itching, redness and painful swelling of lymph nodes. Symptoms can range from mild to severe and usually develop after a few weeks or months of exposure to a triggering factor or agent such as an infection, stress, diet, pollen or chemicals.

Common symptoms include:

• Itching of skin, eyes, ears, nose, and throat.
• Pain and swelling of the lymph nodes in the neck and groin.
• Rashes on the hands, feet, and face.
• Burning or stinging sensation on the skin.
• Hair loss.
• Dryness and cracking of the mucous membranes.
• Rough, dry, scaly skin.
• Depression and fatigue.

The exact cause of MLNS is unknown, but it is believed that the immune system has an abnormal response to a trigger such as infection or stress, resulting in inflammation. The disorder is diagnosed based on symptoms and by excluding other possible causes. Treatment focuses on controlling the symptoms and may include medications such as corticosteroids, antihistamines and immunosuppressants. In some cases, dietary changes and alternative therapies such as acupuncture and stress-management techniques may help.