Infiltrated granuloma annulare lesions

Infiltrated Granuloma Annulare Lesions

Granuloma annulare (GA) is a chronic skin condition characterized by round, raised bumps or lesions on the skin. In some cases, these lesions may become infiltrated with inflammatory cells. When this happens, it is referred to as infiltrated granuloma annulare (IGA). It is important to differentiate between these two forms of granuloma annulare because the treatment and prognosis are different.

IGA lesions tend to be larger and firmer than typical GA lesions, and typically do not respond to most treatments for GA. While the cause of infiltrated granuloma annulare is unknown, it is believed to be related to an autoimmune or allergic reaction in the skin. In some cases, environmental factors, such as ultraviolet (UV) radiation from the sun, may be a factor in its development.

Diagnosis and Treatment of Infiltrated Granuloma Annulare

Infiltrated granuloma annulare is typically diagnosed based on a combination of physical examination and medical history. Your doctor may take a biopsy, or skin sample, to confirm the diagnosis. Imaging tests, such as an X-ray or MRI, may also be used to further evaluate the area.

Treatment typically involves a combination of medications that can reduce inflammation and suppress the immune system. These may include topical steroids, oral steroids, or other immunosuppressant medications. In some cases, cryotherapy or laser therapy may be used to treat the lesions.


In some cases, infiltrated granuloma annulare can lead to complications, including:

  • scarring of the skin
  • ulceration
  • infection of the affected area
  • persistent symptoms