Gestational Trophoblastic Disease

Gestational Trophoblastic Disease (GTD)

Gestational Trophoblastic Disease (GTD) is a rare type of cancer found in pregnant women where abnormal cells in the uterus form a tumor. GTD can have serious consequences for both the mother and fetus. It is important to identify and treat GTD early to ensure successful and healthy pregnancies.

GTD is caused by abnormal cells in the placenta that can develop into a tumor. These cells can also spread throughout the body, including to the lungs and brain. In some cases, the tumor can grow and become malignant.

The most common kind of GTD is called a hydatidiform mole. This kind of mole usually has a yellowish or greyish appearance and often has a large number of fluid filled cysts. Other forms of GTD include choriocarcinoma, placental-site trophoblastic tumors, and epithelioid trophoblastic tumors.

Symptoms of GTD can vary depending on the type of GTD, but typically include:

  • Vaginal bleeding
  • Abdominal pain
  • Low levels of hCG in the blood
  • Low levels of progesterone in the blood
  • Uterine enlargement

If you experience any of these symptoms, it is important to see your doctor right away. Diagnosis of GTD is typically done through an ultrasound or blood test to measure levels of hCG and progesterone.

Treatment for GTD can vary, from surgery to chemotherapy. In some cases, treatment may not be necessary, such as in cases of molar pregnancy.

It is important to remember that GTD is rare and can be treated successfully if caught early. If you believe you may be at risk for GTD, talk to your doctor about the best way to manage your pregnancy.