Discoid Lupus Erythematosus (DLE)

What is Discoid Lupus Erythematosus (DLE)?

Discoid Lupus Erythematosus, also referred to as DLE, is a chronic autoimmune disease in which the body’s immune system mistakenly attacks healthy tissue. It is most commonly characterized by scaly, red, and slightly raised patches on the skin, but can also cause damage to other areas of the body such as organs and joints.

Symptoms of DLE

The most common symptom of DLE is a scaly, red rash on the face that looks like a coin-shaped disc. This rash may worsen with sunlight exposure and heal with treatment. Other symptoms can include:

• Swelling of the joints and surrounding areas.
• Fever, fatigue, and malaise.
• Changes in skin pigmentation.
• Hair loss.
• Blistering or lesions on the skin.
• Permanent scarring of the skin.

Diagnosing DLE

Diagnosis of DLE begins with a physical exam and review of the patient’s medical history. A doctor may also order a skin biopsy to determine if the rash is caused by DLE or another underlying issue.

Treatment of DLE

The primary goal of treating DLE is to reduce inflammation and prevent scarring. Treatment can include:

• Topical creams such as corticosteroids.
• Oral medications such as antimalarials, immunosuppressants, and antibiotics.
• UV light therapy.
• Phototherapy.
• Surgery or biopsies.

In some cases, lifestyle changes such as avoiding sun exposure and wearing protective clothing can help alleviate symptoms of DLE.

Outlook for DLE

With proper treatment, DLE can be successfully managed. However, even with treatment, symptoms may come and go. It is important to follow your doctor’s instructions and practice good self-care to prevent flares of the disease.