Antizoa Tablet, Powder For Suspension

Antizoa, a synthetic antiprotozoal agent. Antizoa is well absorbed from GIT. It interferes with the Pyruvate Ferredoxin Oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic glucose energy metabolism. This results in cell swelling, membrane damage resulting in dysfunction of the parasite.


Antizoa is used for diarrhoea caused by Cryptosporidium parvum and Giardia lamblia, Amebiasis and helminth infections.

Antizoa is also used to associated treatment for these conditions: Ascariasis, Cestode infections, Clostridium difficile infection recurrence, Cryptosporidiosis infection, Diarrhea caused by Cryptosporidium parvum, Diarrhea caused by Giardia lamblia, Giardiasis, Trichuriasis

Trade Name Antizoa
Generic Nitazoxanide
Other Names Nitaxozanid, Nitaxozanide, Nitazoxanida, Nitazoxanide, Nitazoxanidum
Weight 500mg, 100mg/5ml
Type Tablet, Powder For Suspension
Formula C12H9N3O5S
Weight Average: 307.282
Monoisotopic: 307.026291103
Protein binding

Very High (greater than 99%), bound to proteins in the plasma .

Therapeutic Class Anti-diarrhoeal Antiprotozoal
Manufacturer Julphar Bangladesh Ltd
Available Country Bangladesh
Last Updated: June 23, 2021 at 11:23 am


Antizoa dosage

Age 1-3 years: 5 ml (100 mg) twice daily for 3 days

Age 4-11 years: 10 ml (200 mg) twice daily for 3 days

Age >12 years: 25 ml or 1 tablet (500 mg) twice daily for 3 days

The suspension or tablet should be taken with food.

30 ml suspension: Shake the bottle well before adding water. Then add 20 ml of boiled and cooled water (with the help of provided cup) into the bottle and shake well to make 30 ml suspension.

60 ml suspension: Shake the bottle well before adding water. Then add 40 ml of boiled and cooled water (with the help of provided cup) into the bottle and shake well to make 60 ml suspension.

Side Effects

Antizoa is generally well tolerated. However abdominal pain, diarrhoea vomiting and headache have been reported rarely


Antizoa should be administrated with caution to patients with hepatic, renal and biliary disease.


Antizoa is highly bound to plasma protein (>99.9%). Therefore, caution should be used when administering Antizoa concurrently with other highly plasma-protein bound drugs.

Food Interaction

  • Take with food. Food improves oral bioavailability.

Half Life



Antizoa is cleared in the urine and feces. The metabolite, tizoxanide, is also found in the urine, plasma, and breastmilk . The drug is not found unchanged in the urine .

Pregnancy & Breastfeeding use

Pregnancy category B. This drug should be used during pregnancy only if clearly needed.

Nursing mother: It is not known whether Antizoa is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Antizoa is administrated to a nursing woman.


Known hypersensitivity to Antizoa or any other ingredient in the formulations

Special Warning

Paediatric Use: Safety and effectiveness of Antizoa for Oral Suspension in paediatric patients less than one year of age have not been studied.

Impaired renal or hepatic function: The pharmacokinetics of Antizoa in patients with impaired renal or hepatic function have not been studied. Therefore, Antizoa must be administered with caution to patients with hepatic and biliary disease, to patients with renal disease and to patients with combined renal and hepatic disease.

Acute Overdose

Information on Antizoa overdosage is not available. Single oral doses of up to 4000 mg Antizoa have been administered to healthy adult volunteers without significant adverse effects.

Storage Condition

Store in a cool and dry place, away from light and moisture. Once reconstituted suspension should be used within 7 days.

Antizoa contains Nitazoxanide see full prescribing information from innovator Monograph