PBG urine test

What Is a Pyrrole Blood/Urine Test?

A pyrrole blood/urine test is a laboratory test used to detect the presence of excessive levels of pyrroles in a person’s blood or urine. Pyrrole is a small molecule produced during the metabolism of the essential amino acid, tryptophan. When pyrrole levels are excessively high, it can lead to various mental health symptoms, especially those related to depression, bipolar disorder, and attention deficit hyperactivity disorder (ADHD).

Preparing for a Pyrrole Test

No specific preparation is necessary in order to have a pyrrole test. Pyrrole tests are often used in conjunction with other laboratory tests, such as thyroid function tests, hormone tests, and vitamins and essential nutrient levels. In such cases, your doctor may advise you to take certain measures before the tests, which may include fasting and avoiding certain foods or medications.

Procedure for a Pyrrole Test

A pyrrole test is typically done by collecting a sample of blood or urine. The sample is sent to a laboratory for testing. It usually takes about one to two days to get the results. Depending on the laboratory, pyrrole test results are reported in conventional units (such as mg/dL or μg/dL) or as a ratio (such as pyrrole: creatinine).

Types of Pyrrole Tests

Currently, there are two major types of pyrrole tests: the urine pyrrole test and the serum pyrrole test. The urine pyrrole test is a more economical option and requires only a single urine sample. However, the serum pyrrole test is considered to be more accurate. It requires a sample of blood and measures the levels of pyrrole in the serum.

Risks and Complications of a Pyrrole Test

Pyrrole tests are generally considered safe and risk-free. However, some people may experience slight discomfort while giving a blood sample. As with any medical procedure, there is also a very small risk of infection or other complications.

Why Is a Pyrrole Test Done?

A pyrrole test is used to detect the presence of excessive levels of pyrroles in a person’s blood or urine. High levels of pyrroles may indicate the presence of disorders, such as depression, bipolar disorder, and attention deficit hyperactivity disorder (ADHD).

When Is a Pyrrole Test Done?

A pyrrole test is usually done when a person is experiencing mental health symptoms, such as depression, mood swings, and difficulty concentrating. It may also be ordered when other laboratory tests indicate a nutrient deficiency. Pyrrole tests are sometimes done as part of a comprehensive mental health evaluation.