Secondary adrenocortical insufficiency
Secondary Adrenocortical Insufficiency
Secondary adrenocortical insufficiency, also known as adrenal insufficiency or adrenal failure, is a condition in which the adrenal glands do not produce enough cortisol. The adrenal glands are two small glands located on top of the kidneys. They are responsible for producing hormones such as cortisol that are essential for life. Secondary adrenal insufficiency can occur when the pituitary gland or hypothalamus does not produce enough of the hormones that stimulate the adrenal gland to produce cortisol.
Secondary adrenal insufficiency is typically caused by autoimmune diseases such as Addison's disease, infections, or certain medications. Symptoms of secondary adrenal insufficiency may include fatigue, low blood pressure, weight loss, and difficulty tolerating stress.
Treatment of secondary adrenal insufficiency typically involves taking hormone replacement therapy with synthetic cortisol. These drugs help replace the hormones that the body is not producing. Other treatments may include lifestyle changes such as reducing stress, eating a healthy diet, and getting enough rest and exercise.
Symptoms of Secondary Adrenal Insufficiency
- Fatigue
- Low blood pressure
- Weight loss
- Difficulty tolerating stress
- Salt cravings
- Loss of appetite
- Muscle weakness
- Hyperpigmentation (darkening of the skin)
- Changes in mood
- Abdominal pain
- Nausea and vomiting
- Low blood sugar (hypoglycemia)
- Headaches
Treatment of Secondary Adrenal Insufficiency
Treatment of secondary adrenal insufficiency typically involves hormone replacement therapy with synthetic cortisol. These drugs help replace the hormones that the body is not producing. Other treatments may include lifestyle changes such as reducing stress, eating a healthy diet, and getting enough rest and exercise.
It is important to follow your doctor's instructions when taking hormone replacement therapy and to follow up regularly with your doctor to ensure that the hormones are working properly. If not properly managed, secondary adrenal insufficiency can lead to serious complications such as shock, coma, or even death.