Noninfectious Posterior Uveitis

Noninfectious Posterior Uveitis (NIPU) is an inflammatory condition of the back of the eye that can cause severe vision loss. It is the most serious form of uveitis, a general term that refers to swelling or inflammation inside the eye. NIPU is a rare disorder, but it can be serious if not identified and treated early. It is important to understand NIPU and know what to look out for.

Symptoms of Noninfectious Posterior Uveitis

Symptoms of NIPU can include:

Sudden, severe eye pain.
Blurred vision.
Redness in the eye.
Light sensitivity.
Headaches.
Flashes or floaters in the vision.

Causes of Noninfectious Posterior Uveitis

The cause of NIPU is not always known, but it is thought to be an autoimmune response, which means that the immune system mistakenly attacks the eye. Other possible causes include:

Infections such as toxoplasmosis or herpes simplex.
Trauma to the eye.
Inflammation due to other medical conditions such as sarcoidosis or tuberculosis.

Diagnosis and Treatment of Noninfectious Posterior Uveitis

If NIPU is suspected, a doctor will likely use several tests to confirm a diagnosis. These tests can include a slit lamp exam, an ocular ultrasound, and a visual field test. Treatment of NIPU will likely involve medications to reduce inflammation and suppress the immune system. Surgery may also be an option for certain cases.

Prevention of Noninfectious Posterior Uveitis

Since the cause of NIPU is not always known, there is no sure way to prevent it. However, it is important to be aware of the risk factors and keep an eye out for signs and symptoms. Early diagnosis and treatment can help reduce the risk of vision loss. It is also important to practice safe hygiene habits to reduce the risk of infections.