Hepatic Insufficiency

Hepatic Insufficiency is a condition in which the liver fails to perform its normal metabolic functions. This may occur due to a variety of causes, but is most often seen in those with chronic liver diseases such as hepatitis, cirrhosis, and end-stage liver failure. It can be accompanied by jaundice, general abdominal pain, and changes in mental status.

Causes

Hepatic Insufficiency can result from a variety of causes including:

Chronic liver diseases such as hepatitis and cirrhosis
Certain genetic conditions such as Wilson's disease and glycogen storage disease
Alcohol or drug abuse
Certain medications
Exposure to toxins or poisons

Symptoms

Symptoms of Hepatic Insufficiency can include:

Jaundice
Abdominal pain
Nausea
Weight loss
Fatigue
Confusion
Ascites (fluid buildup in the abdomen)

Diagnosis and Treatment

The diagnosis of Hepatic Insufficiency is based on a complete medical history, physical exam, and laboratory tests. Treatment depends on the underlying cause, but may include medications, dietary changes, or in some cases, a liver transplant.