Digoxin toxicity
Digoxin Toxicity
Digoxin toxicity is a condition caused by an overdose of the drug digoxin. It is a common drug used to treat various heart problems, such as atrial fibrillation, heart failure, and control of ventricular rate in supraventricular tachycardia. It works by slowing the heart rate and improving the heart's ability to pump blood. Although this can be a beneficial medication, too much can cause serious symptoms and even be life-threatening.
The most common signs and symptoms of digoxin toxicity include:
- Confusion
- Nausea and vomiting
- Jaundice
- Low blood pressure
- Abnormal heart rhythms, such as bradycardia or tachycardia
- Vision changes, such as blurred vision or yellow-green tint to vision
- Fatigue
- Weakness
- Loss of appetite
- Diarrhea
- Headache
- Light sensitivity
Treatment of digoxin toxicity depends on the severity. Mild symptoms usually only require monitoring, while more severe cases may require supportive treatments such as IV fluids, aggressive electrolyte repletion, and pacing for bradycardia. In addition, there is an antidote available called Digoxin Immune Fab (Digibind), which can be used if necessary.
It’s important for people taking digoxin to be aware of the risks of toxicity. All patients should have frequent lab tests to check serum levels of digoxin in their blood and should always discuss any changes in their symptoms, dosage, or medical conditions with their doctor.