Vapreotidum

Vapreotidum Uses, Dosage, Side Effects, Food Interaction and all others data.

Vapreotidum is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.

Vapreotidum is a somatostatin analog with a higher metabolic stability than the parent hormone. Vapreotidum reduces splanchnic blood flow; inhibits growth hormone release, and inhibits the release of peptides and vasoactive compounds from neuroendocrine tumors.

Table Of contents

• Vapreotidum
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Vapreotidum
Generic	Vapreotide
Vapreotide Other Names	Vapreotida, Vapreotide, Vapreotidum
Type
Formula	C57H70N12O9S2
Weight	Average: 1131.38 Monoisotopic: 1130.48301423
Groups	Experimental, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.

How Vapreotidum works

The exact mechanism of action is unknown, although one study has provided in vitro and in vivo evidence for a tachykinin NK1 receptor antagonist effect in the analgesic effects of vapreotide (PMID: 7556407).

Toxicity

Safety data are limited, however, headache, fatigue, diarrhea, nausea, vomiting, and abdominal pain have been reported commonly with the use of vapreotide.

Half Life

30 minutes

Elimination Route

Vapreotidum is 76% eliminated in bile. The remainder is renally eliminated.

Innovators Monograph

You find simplified version here Vapreotidum