Lyme disease vaccine (recombinant OspA)

Lyme disease vaccine (recombinant OspA) Uses, Dosage, Side Effects, Food Interaction and all others data.

Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant.

OspA lipoprotein is a single polypeptide chain of 270 amino acids. It is a vaccination used to prevent Lyme Disease.

Table Of contents

• Lyme disease vaccine (recombinant OspA)
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Lyme disease vaccine (recombinant OspA)
Generic	Lyme disease vaccine (recombinant OspA)
Lyme disease vaccine (recombinant OspA) Other Names	Lipoprotein OspA antigen recombinant, Lipoprotein outer surface a borrelia burgdorferi antigen, OspA lipoprotein
Type
Formula	C1198H2012N322O422S2
Weight	27743.1 Da
Groups	Approved, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

For prophylactic treatment of Lyme Disease

How Lyme disease vaccine (recombinant OspA) works

OspA lipoprotein, an outer surface protein of the bacteria Borrelia burgdorferi sensu stricto ZS7, is used to stimulate the production of specific antibodies against B. burgdorferi. It is used as a vaccination against Lyme Disease, a disease carried by ticks.

Half Life

1.2 hours (mammalian reticulocytes, in vitro).

Innovators Monograph

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