Magnesium Aluminum Silicate

Magnesium Aluminum Silicate Uses, Dosage, Side Effects, Food Interaction and all others data.

Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group . It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant, andtablet binder. It also has antacid properties and is used as a component of some over the counter antacid medications.

Magnesium aluminum silicate neutralizes excess acid in the stomach to reduce or eliminate symptoms of heartburn, sour stomach, or acid indigestion

Trade Name Magnesium Aluminum Silicate
Generic Magnesium Aluminum Silicate
Magnesium Aluminum Silicate Other Names Aluminii magnesii silicas, Aluminium magnesium silicate, Aluminium magnesium silicate hydrate, Aluminium magnesium silicate polyhydrate, Aluminum magnesium silicate, Magnesium aluminium silicate, Magnesium aluminium silicate hydrate, Magnesium aluminum silicate hydrate
Groups Approved
Therapeutic Class
Available Country
Last Updated: September 19, 2023 at 7:00 am
Magnesium Aluminum Silicate
Magnesium Aluminum Silicate


Magnesium aluminum silicate is used as an over the counter antacid for the self-treatment of heartburn, sour stomach, or acid indigestion .

How Magnesium Aluminum Silicate works

Magnesium aluminum silicate reacts with acid in the stomach to increase the pH.


The LD50 in mice is considered to be >50000 mg/kg with oral suspensions of magnesium aluminum silicate . The dermal LD50 is considered to be >3.5 g/kg observed in rabbits. Magnesium aluminum silicate produced mild skin irritation. In a 90 day study in rats, animal fed a diet with 20% magnesium aluminum silicate had slightly stunted growth. With 5% and 10% the rats had increased silicone content in the spleen. At 2% one male rat died and at 10% one male and female rat died. These rats had fibrous exudates in the thorax and hemorrhage in the lungs with evidence of infection. No evidence of teratogenicity or mutagenicity was found in the appropriate studies.

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