Kurelid Md

Kurelid Md Uses, Dosage, Side Effects, Food Interaction and all others data.

Kurelid Md is a nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, anti-pyretic, and analgesic properties. It inhibits prostaglandin synthetase/cyclooxygenase, which limits prostaglandin production. Its cyclooxygenase inhibiting potency is intermediate, but is relatively selective for the cyclo-oxygenase-2 (COX-2) thus the potential for gastric injury and intolerance is less. It is also a free radical scavenger, and helps protect against the tissue damage that occurs during inflammation.

Food, gender and advanced age have negligible effects on nimesulide pharmacokinetics.

Trade Name Kurelid Md
Generic Nimesulide
Nimesulide Other Names Nimesulida, Nimesulide, Nimesulidum
Type Tablet
Formula C13H12N2O5S
Weight Average: 308.31
Monoisotopic: 308.046692194
Protein binding


Groups Approved, Investigational, Withdrawn
Therapeutic Class Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Manufacturer Rishab Healthcare Ltd
Available Country India
Last Updated: September 19, 2023 at 7:00 am
Kurelid Md
Kurelid Md


Kurelid Md is used for acute pain; extra-articular disorders; osteoarthritis; post-op pain; primary dysmenorrhoea

Kurelid Md is also used to associated treatment for these conditions: Menstrual Distress (Dysmenorrhea), Pain, Pain, Acute, NSAIDs

How Kurelid Md works

The therapeutic effects of Kurelid Md are the result of its complete mode of action which targets a number of key mediators of the inflammatory process such as: COX-2 mediated prostaglandins, free radicals, proteolytic enzymes and histamine.


Kurelid Md dosage

100 mg twice daily.Should be taken with food. Take after meals.

Side Effects

Epigastric discomfort, heartburn or abdominal cramps, nausea, vomiting and diarrhoea; skin rash, pruritus, oedema, headache, dizziness, drowsiness; hypersensitivity reactions (e.g. bronchospasm, rhinitis, angioedema urticaria); GI haemorrhage/perforation; bullous/erosive stomatitis, purpura, thrombocytopenia, toxic epidermal necrolysis, haematuria, oliguria, and renal failure; increases in liver enzymes.


Oral TDLO (human): 1.429 mg/kg; Oral TDLO (woman): 2 mg/kg; Oral LD50 (rat): 200 mg/kg; Oral LD50 (mouse): 392 mg/kg


History of GI tract disease, infections, oedema, hypertension, elderly, lactation.


Additive hepatotoxic effects with known hepatotoxins: anti-convulsants (e.g. valproic acid), anti-fungals (e.g. ketoconazole), anti-tuberculous drugs (e.g. isoniazid), tacrine, pemoline, amiodarone, methotrexate, methyldopa, amoxicillin/clavulanic acid. May decrease the oral bioavailability of furosemide and the natriuretic and diuretic response to furosemide. Increased risks of GI and hepatic adverse effects with other NSAIDs, including aspirin. May increase anti-coagulant effect of warfarin. Potentiates the action of phenytoin. May be displaced from binding sites with fenofibrate, salicylic acid, and tolbutamide. Interactions between NSAIDs and lithium, probenecid and ciclosporin, have been documented.

Elimination Route

Rapidly absorbed following oral administration.

Half Life

1.8–4.7 hours

Elimination Route

Renal (50%), fecal (29%)

Pregnancy & Breastfeeding use

Category not classified


Hypersensitivity; GI bleeding, active peptic ulcer disease; severe renal and heart failure; hepatic impairment or known liver disease; coagulation disorders; pregnancy; children <12 yr.

Acute Overdose

Epigastric pain, nausea, vomiting, drowsiness, lethargy, GI haemorrhage, seizures, hypertension, apnoea, coma, anaphylactic reactions and renal failure. Treatment is supportive.

Storage Condition

Protect from heat and humidity; store at <25°C.

Innovators Monograph

You find simplified version here Kurelid Md


What is Kurelid Md used for?

Kurelid Md is a medication used for pain relief and for the prevention of fever. Acute pain, pain due to menstrual cramps, backache, post-operative pain, osteoarthritis and fever are frequently prescribed.

how safe Kurelid Md is?

It is safer to use one with a favourable benefit-harm balance, such as ibuprofen, when a non-steroidal anti-inflammatory drug is required.The drug is best avoided in known or suspected liver disease; caution is warranted while prescribing nimesulide concomitantly with other hepatotoxic drugs.

What are the common side effect of Kurelid Md ?

Kurelid Md is generally well tolerated, but side effects can include headache, dizziness, somnolence, gastrointestinal upset, nausea, abdominal discomfort, diarrhea, peripheral edema and hypersensitivity reactions.

Is Kurelid Md bad for liver?

Kurelid Md must be withdrawn worldwide due to serious liver damage.Kurelid Md exposes patients to fatal liver damage.

How quickly does Kurelid Md work?

Kurelid Md works rapidly with immediate onset of action when taken orally. It can effectively reduce pain or fever within 15minutes of taking the medicine.

Is Kurelid Md safe during pregnancy?

Our study suggests that the use of Kurelid Md in early pregnancy may result in a greater risk of having births with congenital urinary tract anomalies.

Can I take Kurelid Md while breastfeeding?

The action of Kurelid Md on milk production for infants or the composition of milk is currently unknown. Some studies also suggest that Kurelid Md is unsafe for lactating women., lactating women are advised to take medical expert advice, take this drug with precautions, and avoid long-term use.

Can I take Kurelid Md safe with alcohol?

Avoid consuming alcohol while taking Kurelid Md as it can increase your risk of stomach problems.

Does bnrand increase blood pressure?

Our results indicate no difference between Kurelid Md and ketoprofen effects on mean blood pressure values during antihypertensive therapy.

Can Kurelid Md be taken empty stomach?

Do not take it on an empty stomach.Always take Kurelid Md together with food or immediately after a meal.

Is Kurelid Md safe for kidneys?

This observation indicates that Kurelid Md can provoke acute renal failure as a result of an obstructive crystalline nephropathy.

Can heart patients take Kurelid Md?

Kurelid Md should be used with great caution in patients with compromised renal function, cirrhosis of liver, congestive heart failure, renovascular disease, volume or salt depletion.

Is Kurelid Md good for headache?

Kurelid Md with Paracetamol is used for pain relief.

Is Kurelid Md used for migraine?

Kurelid Md has a well documented efficacy for relieving symptoms associated with migraine and non-migraine headaches.

Can Kurelid Md I take in periods?

Kurelid Md reduces the pressure during the maximal but not during the submaximal pain period, with concomitant alleviation of pain. The drug changes the painful state of uterine contracture to painless cyclic contractions.

Can Kurelid Md use for ear pain?

Kurelid Md indicate that the drug may be an effective and well tolerated therapy for painful inflammatory conditions of the ear, nose and throat.

Can Kurelid Md cause sleepiness?

Kurelid Md suspension overdose can make you drowsy (feeling sleepy).Generally suspension does not make you feel drowsy. 

Can Kurelid Md be used for throat pain?

Kurelid Md which may be prescribed by your doctor to get rid of a sore throat and fever if you get these symptoms.

Is Kurelid Md safe for adults?

Kurelid Md may safe for adult if Kurelid Md recommended dose in 100 mg twice daily for no more than 15 days.

How bad is bnand?

Kurelid Md must be withdrawn worldwide due to serious liver damage.It exposes patients to fatal liver damage.

Can I take Kurelid Md for a long time?

Kurelid Md is not recommended long-term, as for chronic conditions such as arthritis. This is due to its association with an increased risk of liver toxicity, including liver failure.

Can I drive after taking Kurelid Md?

Kurelid Md may cause dizziness. If you feel dizzy, do not drive or take part in any activity in which you need to be alert.

*** Taking medicines without doctor's advice can cause long-term problems.